Key result
Left ventricular geometry significantly influenced right ventricular function in hypertensive patients, with RV remodeling most pronounced in concentric and dilated LVH patterns.
Why the study?
How does left ventricular geometry influence right ventricular structure and function in hypertensive patients?
Cross-Sectional (n=232)
How does left ventricular geometry influence right ventricular structure and function in hypertensive patients?
Right ventricular remodeling and dysfunction are significantly influenced by left ventricular geometry in hypertensive patients, being most pronounced in concentric, dilated, and concentric-dilated LVH.
RV remodeling varies by LV geometry in hypertension; hypothesis-generating, prospective data needed before clinical adoption.
OBJECTIVE: We sought to evaluate right ventricular (RV) structure and function in hypertensive patients with various left ventricular (LV) geometric patterns using an updated classification for LV geometry. METHODS: This cross-sectional study included 232 hypertensive subjects. All the subjects underwent complete two-dimensional (2D) and three-dimensional (3D) echocardiographic examination. Using LV mass index, LV end-diastolic diameter and relative wall thickness, according to the updated classification, all subjects were divided into six different groups: normal LV geometry, concentric remodeling, eccentric LV hypertrophy (LVH), concentric, dilated, and concentric-dilated LVH. RESULTS: RV wall thickness was increased in concentric and concentric-dilated LVH compared with normal LV geometry and LV concentric remodeling. RV longitudinal function was reduced in concentric and concentric-dilated patients compared with other hypertensive groups. 3D RV volumes were significantly higher in eccentric, dilated, and concentric-dilated LVH hypertensive subjects. Conversely, 3D RV ejection fraction was lower in these groups. CONCLUSION: RV longitudinal myocardial function and 3D RV function are significantly influenced by LV geometry in hypertensive patients. RV remodeling is the most pronounced in the patients with concentric, dilated, and concentric-dilated LVH geometric patterns.
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Tadić et al. (2016) conducted a cross-sectional in Hypertension (n=232). Left ventricular geometric patterns vs. Normal LV geometry was evaluated on Right ventricular structure and function. Left ventricular geometry significantly influenced right ventricular function in hypertensive patients, with RV remodeling most pronounced in concentric and dilated LVH patterns.
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