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Accepted Answer

GLP-1 receptor agonists and tirzepatide act primarily as metabolic optimizers that secondarily enhance female fertility by improving body weight, insulin resistance, and hyperandrogenism, though evidence for direct reproductive effects and periconceptional safety remains insufficient. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

The Impact of GLP-1 Analogues and Tirzepatide on Female Fertility: Mechanisms, Clinical Evidence, and Implications

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