Key result
The echocardiography-derived S′/RAAi ratio accurately detected elevated right ventricular end-diastolic elastance (AUC 0.913; 95% CI 0.839-0.986) and predicted prognosis in pulmonary hypertension.
Why the study?
Right ventricular diastolic dysfunction may be prognostic in pulmonary hypertension, but its assessment is complex and relies on conductance catheterisation.
Does the echocardiography-derived S′/RAAi ratio accurately detect right ventricular diastolic dysfunction and predict survival in patients with pulmonary hypertension?
Observational (n=392)
Yes
Does the echocardiography-derived S′/RAAi ratio accurately detect right ventricular diastolic dysfunction and predict survival in patients with pulmonary hypertension?
Effect estimate: AUC 0.913 (95% CI 0.839-0.986)
The echocardiography-derived S′/RAAi ratio provides a highly accurate, noninvasive surrogate for right ventricular diastolic function and is prognostically relevant in pulmonary hypertension.
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S′/RAAi may aid noninvasive RV diastolic assessment in PH; leaves open prospective validation before clinical adoption.
Yogeswaran et al. (2023) conducted an observational in Pulmonary hypertension (n=392). Peak lateral tricuspid annulus systolic velocity/right atrial area index ratio (S′/RAAi) vs. Standard echocardiographic parameters (E/A and E/e' ratios) was evaluated on Detection of elevated end-diastolic elastance (Eed) (AUC 0.913, 95% CI 0.839-0.986). The echocardiography-derived S′/RAAi ratio accurately detected elevated right ventricular end-diastolic elastance (AUC 0.913; 95% CI 0.839-0.986) and predicted prognosis in pulmonary hypertension.
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