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This study aims to define the mortality and morbidity associated with nonconvulsive status epilepticus (NCSE) and its relation to various causes.

October 28, 2003Neurology

Assessment of acute morbidity and mortality in nonconvulsive status epilepticus

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This study aims to define the mortality and morbidity associated with nonconvulsive status epilepticus (NCSE) and its relation to various causes.
Retrospective analysis of 100 patients with NCSE from an EEG database.
Systematic review of medical records and EEG tracings to determine specific etiologies.
Categorization of etiologies into acute medical, epilepsy, and cryptogenic groups.
Out of 100 patients, 18 died during the study.
Mortality rates were significantly higher in the acute medical group (27%) compared to the epilepsy (3%) and cryptogenic (18%) groups (p < 0.02).
Severe mental status impairment correlated with a mortality rate of 39%, while mild impairment had a rate of 7% (p < 0.001).

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Retrospective analysis finds high mortality linked to acute causes and severe impairment in NCSE patients, indicating treatment urgency.

Shneker et al. (2003) studied this question.

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