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The wonderful versatility of dendritic structures is demonstrated by their ability to act as efficient gene transfection vectors. This review will tell the story of how dendrimers came to be exploited for gene delivery, outline the different types of structures that have proven to be successful vectors and demonstrate how structural variation is being used as a tool to increase efficiency and probe structure–activity relationships.
Guillot-Nieckowski et al. (Fri,) studied this question.