Kimura’s disease sequentially involving multiple sites in the head and neck: A case report with a 13-year follow-up and literature review

Figures

• 

  Figure 1.. Preoperative facial photographs.

• 

  Figure 2.. Plain computed tomography of the neck.

• 

  Figure 3.. Glands and masses removed during surgery.

• 

  Figure 4.. Postoperative pathology (hematoxylin and eosin staining, 400×). Follicular hyperplasia was noted in the left submandibular lymph node, a large number of eosinophil infiltrates were observed in the paracortical area between the follicles and capsule, and the capsule was thickened and the surrounding salivary gland was infiltrated by lymphocytes.

• 

  Figure 5.. Orbital magnetic resonance imaging-1. The bilateral eyeball morphology was normal, the left eyeball protruded slightly more anteriorly than the right eyeball, there was no obvious abnormal signal shadow in the orbit, the lens was in place, the optic nerve was not altered, and the left subocular rectus muscle was thickened.

• 

  Figure 8.. Orbital magnetic resonance imaging-2.

• 

  Figure 9.. Findings before treatment (29 January 2024).

• 

  Figure 11.. Timeline of disease progression.

• 

  Figure 6.. Sagittal orbital computed tomography. The left optic nerve was partially thickened, and a soft tissue mass was observed in the posterior frame of the eyeball, approximately 2.8 cm × 1.6 cm in size, with smooth edges and unclear boundaries with the optic nerve. The left eyeball protruded slightly outward, with uniform intrabulbar density. The right eye ring was continuous and complete, the shape of the eyeball was normal, the density of the bulb was uniform, the lens was in place, the anterior chamber was clear, the density of the extraocular muscles was uniform, there was no swelling, no obvious abnormality was observed in the interruption of the right optic nerve, and the retrobulbar fat gap was clear.

• 

  Figure 7.. Horizontal orbital computed tomography.

• 

  Figure 10.. Findings after treatment (14 February 2024). Bilateral eye asymmetry, swelling of the skin around the left eye with normal color, and protrusion of the left eyeball were observed.