Key result
Oral corticosteroid therapy led to a marked decrease in the size of orbital and facial swellings and disappearance of hyperpigmentation in a 23-year-old female with Kimura's disease.
Case Report (n=1)
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Kimura's disease rarely affects the orbit but should be considered in the differential diagnosis of inflammatory orbital diseases.
A 23 year female presented with bilateral recurrent swelling of eyelids along with ptosis and proptosis for last 3 years. She also had swellings over the right cheek, parotid gland, and retro auricular area along with regional lymphadenopathy. Systemic laboratory workup revealed raised serum IgE and a high peripheral eosinophil count. Computed tomography and magnetic resonance imaging showed bilateral enlargement of extraocular muscles, lacrimal glands, and ipsilateral parotid gland. Excision biopsy of the retro-auricular lymph node was suggestive of Kimura's disease (KD). The patient responded well to systemic corticosteroid. KD rarely affects orbit, but it should be included in the differential diagnosis of inflammatory diseases of the orbit. To our knowledge, this is the first reported case of KD from India involving the orbit, lacrimal gland, extraocular muscles, parotid gland and buccal area.
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Chakraborti et al. (2019) conducted a case report in Kimura's disease (n=1). Oral prednisolone was evaluated on Clinical response (reduction in swelling and hyperpigmentation). Oral corticosteroid therapy led to a marked decrease in the size of orbital and facial swellings and disappearance of hyperpigmentation in a 23-year-old female with Kimura's disease.
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