April 1, 2008Heart
Should the first priority in cardiovascular risk management be those with prior cardiovascular disease?
Key result
Prior cardiovascular disease was associated with an approximately 20% higher absolute 5-year risk of cardiovascular events compared to no prior disease, adjusting for standard risk factors.
Why the study?
Does prior cardiovascular disease increase the risk of future CVD events beyond standard risk factors in primary care patients?
Population
35,760 patients assessed in routine primary care, including 10.4% with prior cardiovascular disease (CVD)
Comparison
Prior cardiovascular disease (CVD) vs No prior cardiovascular disease (CVD)
Design
Cohort
Follow-up
average 2.05 years
Authors
Discussion
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Member takes
Implication
Supports prioritizing secondary prevention patients; extends standard risk equations by quantifying prior CVD's independent prognostic contribution.
Study Design
Type
Cohort (n=35,760)
Multicenter
Yes
Structured PICO
Does prior cardiovascular disease increase the risk of future CVD events beyond standard risk factors in primary care patients?
P
Population
35,760 primary care patients assessed for cardiovascular risk and followed for an average of 2.05 years.
E
Exposure
Prior cardiovascular disease (CVD)
C
Comparator
No prior cardiovascular disease (CVD)
O
Outcome
First CVD eventshard clinical
Patients with prior CVD have significantly higher absolute risks of future CVD events independent of standard risk factors, reinforcing their priority for intensive preventive management.
Cite This Study
Kerr et al. (2008) conducted a cohort in Cardiovascular disease risk (n=35,760). Prior cardiovascular disease vs. No prior cardiovascular disease was evaluated on First CVD events. Prior cardiovascular disease was associated with an approximately 20% higher absolute 5-year risk of cardiovascular events compared to no prior disease, adjusting for standard risk factors.