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July 24, 2026The Journal of Urology

Efficacy and Tolerability of Overnight Bladder Drainage post Posterior Urethral Valve Ablation on Upper and Lower Urinary Tracts: A Randomized Controlled Trial

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Authors

AEAhmed ElkashefMansoura UniversityAAAhmed ABDELHALIMWest Virginia UniversityMDMohamed DawabaMansoura University

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Implication

Randomized trial shows overnight bladder drainage improves urinary tract outcomes in boys, indicating its potential benefit.

Key Points

  • To assess the impact of overnight bladder drainage on urinary tract health in boys after valve ablation.
  • Randomized controlled trial including 99 patients (47 with OBD, 52 without OBD) from September 2021 to August 2023.
  • Utilized Tc-dimercaptosuccinic acid scans to evaluate renal function and urinary tract health.
  • Monitored for febrile urinary tract infections and assessed tolerability to overnight bladder drainage.
  • Overnight bladder drainage resulted in significant improvements in hydronephrosis (HN), vesicoureteral reflux (VUR), renal parenchymal area, bladder capacity, and daytime continence.
  • No significant differences observed in bladder wall thickness or renal function.
  • Tolerability to overnight bladder drainage was reported at 87%.

Cite This Study

Elkashef et al. (2026) studied this question.

synapsesocial.com/papers/6a62ffef395161722cd15220https://doi.org/10.1097/ju.0000000000005226
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1PD04-01 EFFECT OF OVERNIGHT BLADDER DRAINAGE ON POSTERIOR URETHRAL VALVE SEQUELAE: A RANDOMIZED CONTROLLED TRIAL2024 · 1 citations
  2. 2Correlation of Urodynamic Parameters to Long-term Outcomes Following Posterior Urethral Valve Fulguration2024
  3. 3Bladder Dysfunction in Children with Primary Vesicoureteral Reflux: Do We Need to Change Indications for Surgery?2025
  4. 4Efficacy and Safety of Low-Dose Intravesical OnabotulinumtoxinA Injections in Female Patients With Detrusor Overactivity With Detrusor Underactivity2024 · 1 citations
  5. 5Bladder Function Associated With Posterior Urethral Valves After Primary Valve Ablation or Proximal Urinary Diversion in Children and Adolescents2002 · 31 citations