The Makowiec Generalised Asymmetry Index applied to daytime blood pressure signals may serve as a noninvasive marker supporting obstructive sleep apnea screening and risk stratification.
Observational
Does the Makowiec Generalised Asymmetry Index of daytime HRV and BPV differentiate between healthy men and patients with obstructive sleep apnea?
The Makowiec Generalised Asymmetry Index applied to daytime blood pressure variability may serve as a novel noninvasive marker for OSA screening and risk stratification.
Abstract The Makowiec Generalised Asymmetry Index, denoted by {\, MI\, } (q) MI (q), is a q -parameterised family of directional asymmetry measures for time series, computed from short-term recordings to quantify the imbalance between opposite changes (increases vs. decreases) across fluctuation magnitudes. In this study, we apply the Makowiec Generalised Asymmetry Index to daytime recordings of heart rate variability (HRV) and blood pressure variability (BPV) collected during wakefulness, and we evaluate its usefulness for the characterization of healthy men and obstructive sleep apnea (OSA) patients. Our findings suggest that asymmetry quantified by the Makowiec Generalised Asymmetry Index in daytime for blood pressure signals during wakefulness may serve as a noninvasive marker supporting OSA screening and risk stratification, motivating further validation in larger prospective cohorts.
Graff et al. (Wed,) conducted a observational in Obstructive sleep apnea. Makowiec Generalised Asymmetry Index was evaluated on Characterization of healthy men and obstructive sleep apnea (OSA) patients. The Makowiec Generalised Asymmetry Index applied to daytime blood pressure signals may serve as a noninvasive marker supporting obstructive sleep apnea screening and risk stratification.