Key result
Male acute coronary syndrome patients with diabetes mellitus were significantly less likely to experience chest pain radiating to the neck compared to non-diabetic patients (3.0% vs 21.4%, p=0.025).
Why the study?
Atypical chest pain symptoms in ACS can be ambiguous in patients with diabetes mellitus, potentially leading to prehospital delay and late treatment.
Do chest pain symptom characteristics differ between diabetes mellitus and non-diabetes mellitus patients presenting with acute coronary syndrome?
Cross-Sectional (n=61)
No
Do chest pain symptom characteristics differ between diabetes mellitus and non-diabetes mellitus patients presenting with acute coronary syndrome?
Absolute Event Rate: 3% vs 21.4%
p-value: p=0.025
Patients with diabetes mellitus and acute coronary syndrome present with less severe and more atypical chest pain compared to non-diabetic patients, emphasizing the need for high clinical suspicion in this high-risk group.
Warrants caution interpreting neck radiation in diabetic males with ACS; leaves open validation in prospective symptom studies.
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Manistamara et al. (2021) conducted a cross-sectional in Acute Coronary Syndrome (n=61). Diabetes Mellitus vs. Non-Diabetes Mellitus was evaluated on Chest pain radiating to the neck (p=0.025). Male acute coronary syndrome patients with diabetes mellitus were significantly less likely to experience chest pain radiating to the neck compared to non-diabetic patients (3.0% vs 21.4%, p=0.025).
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