Key result
Lower preprocedural left atrial appendage upward wall-motion velocity was associated with AF recurrence within 1 year after catheter ablation (OR 1.45; 95% CI 1.13-2.01; P=0.009).
Why the study?
Does preprocedural LAA wall-motion velocity predict recurrence of AF within 1 year after catheter ablation in patients with nonparoxysmal AF?
Cohort (n=41)
No
Does preprocedural LAA wall-motion velocity predict recurrence of AF within 1 year after catheter ablation in patients with nonparoxysmal AF?
Preprocedural LAA upward wall-motion velocity assessed by transesophageal echocardiography may serve as a useful independent predictor of AF recurrence within 1 year after catheter ablation for nonparoxysmal AF.
Answers are grounded in this paper and cite their sources.
May support preablation risk stratification in nonparoxysmal AF; leaves open prospective validation before guiding decisions.
Catheter ablation (CA) for nonparoxysmal atrial fibrillation (AF) is controversial due to its high recurrence rate. The aim of this study was to assess retrospectively the diagnostic value of preprocedural left atrial appendage (LAA) wall-motion velocity in predicting recurrence of AF within 1 year after CA. We hypothesized that tissue Doppler-derived measurement of LAA wall-motion velocity associate with recurrence of AF within 1 year after CA. We retrospectively reviewed 47 consecutive patients with nonparoxysmal AF (defined as AF lasting for 1 week or longer) who underwent both transthoracic and transesophageal echocardiography before their first treatment by CA in a single center. Forty-one patients aged 58 ± 10 years were included, and variables predicting the recurrence of AF within 1 year after CA were evaluated. Seventeen patients (41%) developed recurrence of AF within 1 year after CA. Univariate analyses showed that preprocedural LAA upward wall-motion velocity at the apex assessed by transesophageal echocardiography was significantly lower in patients with recurrence of AF than those without recurrence (OR = 1.45, 95% CI: 1.13-2.01, P = 0.009). Multivariate logistic analyses including other potential predictors (duration of AF, left ventricular ejection fraction, E-wave deceleration time, and left atrial wall-motion velocity) identified LAA upward wall-motion velocity at the apex as an independent predictor of outcome. These data suggest in patients with nonparoxysmal AF, preprocedural LAA upward wall-motion velocity at the apex, as determined by tissue Doppler imaging during transesophageal echocardiography, may be a useful indicator for predicting recurrence of AF within 1 year after CA.
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Ariyama et al. (2014) conducted a cohort in Nonparoxysmal atrial fibrillation (n=41). Preprocedural left atrial appendage upward wall-motion velocity was evaluated on Recurrence of AF within 1 year after catheter ablation (OR 1.45, 95% CI 1.13-2.01, p=0.009). Lower preprocedural left atrial appendage upward wall-motion velocity was associated with AF recurrence within 1 year after catheter ablation (OR 1.45; 95% CI 1.13-2.01; P=0.009).
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