Intrauterine adhesions, a leading cause of infertility worldwide

Intrauterine adhesions, a leading cause of infertility worldwide Dr. Angelo Hooker from Zaans Medical Center (ZMC) discusses the causes, impacts, and ways forward for the prevention of intrauterine adhesions (IUAs). Intrauterine adhesions (IUAs) are a common gynecological condition characterized by bands of fibrous scar tissue that partially or completely obliterate the uterine cavity. (1) In 1894, the first case of IUAs was reported, and fifty years later, Asherman described the etiology and symptomatology of IUAs. (2,3) Joseph Asherman described the etiology, frequency, and symptoms of IUAs in 1948, which have since then been known as the Asherman syndrome. (3) The terms IUAs and Asherman syndrome are often used interchangeably, although the syndrome requires signs and symptoms. (4,5) IUAs have a debilitating impact on the health and quality of life in women of childbearing age, while the economic burden is substantial. (4,6)