Key result
Interventions on both atrioventricular valves (SHR 2.1; 95% CI 1.2-3.8) and preoperative right bundle branch block (SHR 7.0; 95% CI 3.9-12.4) independently predicted long-term pacemaker implantation.
Why the study?
Bradyarrhythmia requiring pacemaker implantation after valve surgery may occur even after several years, but its predictors remain unclear.
What are the electrocardiographic and surgical predictors of long-term atrioventricular block requiring pacemaker implantation following valve surgery?
Cohort (n=1,046)
No
What are the electrocardiographic and surgical predictors of long-term atrioventricular block requiring pacemaker implantation following valve surgery?
Hazard Ratio: 2.1 (95% CI 1.2–3.8)
p-value: p=0.014
Pre-operative atrioventricular conduction disease (especially right bundle branch block) and combined surgery on both atrioventricular valves strongly predict the need for long-term pacemaker implantation after valve surgery.
Patients after valve surgery warrant extended monitoring for late pacemaker need; leaves open prospective validation of predictors.
Background: Bradyarrhythmia requiring pacemaker implantation among patients undergoing valve surgery may occur even after several years, with unclear predictors. Our aim was to investigate the incidence of pacemaker implantation at different follow-up times and identify associated predictors. Methods: We conducted a retrospective study evaluating 1046 consecutive patients who underwent valve surgery at the Cardiac Surgery Division of Bologna University Hospital from 2005 to 2010. Results: During 10 ± 4 years of follow-up, 11.4% of these patients required pacemaker implantation. Interventions on both atrioventricular valves independently predicted long-term pacemaker implantation (SHR 2.1, 95% CI 1.2–3.8, p = 0.014). Preoperative atrioventricular conduction disease strongly predicted long-term atrioventricular block, with right bundle branch block as the major predictor (SHR 7.0, 95% CI 3.9–12.4, p < 0.001), followed by left bundle branch block (SHR 4.9, 95% CI 2.4–10.1, p < 0.001), and left anterior fascicular block (SHR 3.9, 95% CI 1.8–8.3, p < 0.001). Conclusion: Patients undergoing valvular surgery have a continuing risk of atrioventricular block late after surgery until the 12-month follow-up, which was clearly superior to the rate of atrioventricular block observed at long-term. Pre-operative atrioventricular conduction disease and combined surgery on both atrioventricular valves are strong predictors of atrioventricular block requiring pacemaker implantation.
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Farina et al. (2024) conducted a cohort in Valvular heart disease requiring surgery (n=1,046). Interventions on both atrioventricular valves vs. Single valve surgery or no preoperative conduction disease was evaluated on Long-term pacemaker implantation (SHR 2.1, 95% CI 1.2-3.8, p=0.014). Interventions on both atrioventricular valves (SHR 2.1; 95% CI 1.2-3.8) and preoperative right bundle branch block (SHR 7.0; 95% CI 3.9-12.4) independently predicted long-term pacemaker implantation.
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