Key result
Despite radical nephrectomy and multiple lines of adjuvant chemotherapy, the patient experienced rapid disease progression with pleuropulmonary metastases and died 13 months after diagnosis.
Case Report (n=1)
No
Primary renal angiosarcoma is an extremely rare and aggressive malignancy with a poor prognosis despite surgical and adjuvant treatment.
Supports known poor prognosis of primary renal angiosarcoma; leaves open identification of effective systemic therapies.
Angiosarcoma is an extremely rare, high-grade malignancy, which accounts for <2% of all soft-tissue sarcomas. Cases of primary renal angiosarcoma represent 1% of these. Angiosarcomas involving the kidney usually originate from metastatic skin lesions or primary visceral lesions and most often occur in the sixth and seventh decades of life. The present study describes a case of primary renal angiosarcoma that presented as a large right-sided renal mass with symptoms of flank pain. Despite surgical removal of the tumor, recurrent disease with associated lung metastases was identified at the surgical site following adjuvant chemotherapy. The patient succumbed to the disease 13 months after the diagnosis.
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Çelebi et al. (2015) conducted a case report in Primary renal angiosarcoma (n=1). Surgical resection and adjuvant chemotherapy was evaluated on Survival and disease progression. Despite radical nephrectomy and multiple lines of adjuvant chemotherapy, the patient experienced rapid disease progression with pleuropulmonary metastases and died 13 months after diagnosis.
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