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This research aims to identify the types and rates of cancers associated with HIV infection in hemophilia patients.

February 26, 1992JAMA

Incidence of Lymphomas and Other Cancers in HIV-Infected and HIV-Uninfected Patients With Hemophilia

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This research aims to identify the types and rates of cancers associated with HIV infection in hemophilia patients.
Cohort analytic study design with HIV-infected and uninfected subjects
Follow-up duration of up to 12 years
Total of 1701 hemophilia patients, 1065 of whom were HIV-1 seropositive.
Incidence of non-Hodgkin's lymphoma in HIV-positive patients post-seroconversion: 0.15 cases per 100 person-years (95% CI, 0.08 to 0.25)
200-fold increased incidence of Kaposi's sarcoma in HIV-positive subjects (95% CI, 20 to 700)
No significant increase in cancer incidence for cancers other than lymphoma and Kaposi's sarcoma in HIV-positive subjects (observed to expected ratio 0.9, 95% CI, 0.4 to 1.9).

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Cohort analytic study investigates cancer rates in hemophilia patients with HIV, revealing significant lymphoma risk.

Charles S. Rabkin (1992) studied this question.

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