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October 17, 2008Journal of Applied Physiology183 citations

Aerobic exercise training reduces epicardial fat in obese men

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MKMaeng-Kyu KimTTTsugio TomitaMKMi-Ji Kim

Key Result

A 12-week aerobic exercise training program significantly reduced ventricular epicardial fat thickness in obese middle-aged men (P<0.001).

Structured PICO

Does a 12-week aerobic exercise training program reduce epicardial fat thickness in obese middle-aged men?

P
Population
24 obese middle-aged men who completed a 12-week supervised aerobic exercise training program.
I
Intervention
12-week supervised aerobic exercise training program (60-70% of maximal heart rate; 60 min/day, 3 days/wk)
O
Outcome
Change in ventricular epicardial fat thickness measured by transthoracic echocardiographysurrogate

A 12-week aerobic exercise training program significantly reduces ventricular epicardial fat thickness and visceral adipose tissue in obese middle-aged men.

Main Result

p-value: p=<0.001

Abstract

The purpose of this study was to determine the effects of exercise training on ventricular epicardial fat thickness in obese men and to investigate the relationship of the change in epicardial fat thickness to changes in abdominal fat tissue following exercise training. Twenty-four obese middle-aged men age, 49.4 +/- 9.6 yr; weight, 87.7 +/- 11.2 kg; body mass index (BMI), 30.7 +/- 3.3 kg/m(2); peak oxygen consumption, 28.4 +/- 7.2 ml.kg(-1).min(-1); means +/- SD participated in this study. Each participant completed a 12-wk supervised exercise training program (60-70% of the maximal heart rate; 60 min/day, 3 days/wk) and underwent a transthoracic echocardiography. The epicardial fat thickness on the free wall of the right ventricle was measured from both parasternal long- and short-axis views. The visceral adipose tissue (VAT) and subcutaneous adipose tissues were measured by computed tomography. Following exercise training, the epicardial fat thickness was significantly decreased (P < 0.001). The percentage change of epicardial fat thickness was twice as high compared with those of waist, BMI, and body weight of original values (P <0.05). There was a significant relationship (r = 0.525, P = 0.008) between changes in the epicardial fat thickness and VAT with exercise training. Stepwise multiple regression analysis revealed that the change in VAT, change in systolic blood pressure, and change in quantitative insulin sensitivity check index were independently related to the change epicardial fat thickness (P < 0.05). The ventricular epicardial fat thickness is reduced significantly after aerobic exercise training and is associated with a decrease in VAT. These results suggest that aerobic exercise training may be an effective nonpharmacological strategy for decreasing the ventricular epicardial fat thickness and visceral fat area in obese middle-aged men.

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Cite This Study

Kim et al. (2008) studied Obesity (n=24). Aerobic exercise training was evaluated on Ventricular epicardial fat thickness (p=<0.001). A 12-week aerobic exercise training program significantly reduced ventricular epicardial fat thickness in obese middle-aged men (P<0.001).

synapsesocial.com/papers/6a6327bec1d5a33248095728https://doi.org/10.1152/japplphysiol.90756.2008
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