Key result
A 12-week endurance and strength training program in overweight men significantly reduced cardiac lipid content (0.99% to 0.54%, P=0.02) and improved ejection fraction (52.2% to 54.2%, P=0.02).
Why the study?
Does a 12-week supervised training program improve cardiac lipid content and systolic function in healthy, male overweight/obese subjects?
Population
14 healthy, male overweight/obese subjects (mean age 58.4 +/- 0.9 yr, body mass index 29.9 +/- 0.01 kg/m2)
Design
Cohort
Follow-up
12 weeks
Authors
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May support exercise to reduce cardiac steatosis in overweight men; hypothesis-generating and requires randomized confirmation before practice change.
Does a 12-week supervised training program improve cardiac lipid content and systolic function in healthy, male overweight/obese subjects?
Absolute Event Rate: 54.2% vs 52.2%
p-value: p=0.02
A 12-week exercise training program in overweight men reduced cardiac lipid content and improved left ventricular ejection fraction, suggesting a potential reversal of cardiac lipotoxicity.
Schrauwen‐Hinderling et al. (2010) studied Overweight/Obesity (n=14). Supervised training program (endurance and strength training) vs. Baseline (pre-training) was evaluated on Maximal whole-body oxygen uptake, fasting plasma parameters, systolic function, and cardiac lipid content (p=0.02). A 12-week endurance and strength training program in overweight men significantly reduced cardiac lipid content (0.99% to 0.54%, P=0.02) and improved ejection fraction (52.2% to 54.2%, P=0.02).
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