Key result
Female sex was associated with a higher lifetime prevalence of Major Depressive Disorder compared to males (11.5% vs 4.3%, OR 2.6), and higher antidepressant use among those with MDD (57% vs 38%).
Population
3,398 adults randomly drawn from municipal records in 7 centres of 6 Italian regions
Design
Cross-sectional
Authors
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Highlights sex disparity in MDD; leaves open whether targeted screening improves outcomes.
Cross-Sectional (n=3,398)
Yes
Odds Ratio: 2.6
Absolute Event Rate: 11.5% vs 4.3%
p-value: p=0.0001
Carta et al. (2010) conducted a cross-sectional in Major Depressive Disorder (n=3,398). Female sex vs. Male sex was evaluated on Lifetime prevalence of Major Depressive Disorder (OR 2.6, p=0.0001). Female sex was associated with a higher lifetime prevalence of Major Depressive Disorder compared to males (11.5% vs 4.3%, OR 2.6), and higher antidepressant use among those with MDD (57% vs 38%).
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