Key result
Among depressed acute coronary syndrome patients who did not participate in secondary prevention, impaired positive relations were associated with a significantly higher frequency of cardiac events (50% vs 13%).
Why the study?
Most studies have focused on the unitary construct of psychological well-being, neglecting the role played by distinct dimensions on cardiac course after acute coronary syndrome.
Do unbalanced levels of psychological well-being dimensions affect participation in secondary prevention and cardiac prognosis in depressed ACS patients?
Cohort (n=136)
Yes
Do unbalanced levels of psychological well-being dimensions affect participation in secondary prevention and cardiac prognosis in depressed ACS patients?
Absolute Event Rate: 50% vs 13%
p-value: p=0.031
Both high and low levels of specific psychological well-being dimensions can negatively impact participation in secondary prevention and cardiac prognosis in depressed ACS patients.
PWB dimension findings post-ACS are hypothesis-generating; prospective trials needed before considering targeted support in rehabilitation.
Literature supports the positive effects of psychological well-being (P.W.B.) on health. However, most studies focused on the unitary construct of P.W.B., neglecting the different role played by distinct P.W.B. dimensions on health-related outcomes. The aim of this study was to determine whether unbalanced (i.e. low or high) levels of P.W.B. dimensions could differentially affect cardiac course after acute coronary syndrome (A.C.S.), in terms of participation in secondary prevention (S.P.) and/or survival. The sample included 136 depressed and/or demoralized A.C.S. patients referred for a S.P. program on lifestyle modification, in addition to routine cardiac visits provided by the hospital where they were admitted. Psychological assessment included validated interviews on depression and demoralization, Symptom Questionnaire and Psychological Well-Being scales. 100 patients joined the S.P. program, 36 did not. Logistic regression revealed that older age (B = 0.051; p < 0.05), higher autonomy (B = 0.070; p < 0.05) and lower personal growth (B = −0.073; p < 0.05) levels were associated with non-participation in S.P. Moreover, only among patients who did not join the program, those presenting with an impaired level of P.W.B. ‘positive relations’ dimension (i.e. below the 25th percentile) showed a worse cardiac prognosis (Log Rank: χ2(1) = 4.654; p = 0.031). Negative health outcomes in depressed cardiac patients, such as non-participation in S.P. and worse cardiac course, are associated with both high and low levels of certain P.W.B. dimensions. Psychotherapeutic approaches geared to a balance in P.W.B. dimensions could represent promising new additions to S.P. programs.
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Gostoli et al. (2021) conducted a cohort in Acute coronary syndrome with depression and/or demoralization (n=136). Impaired positive relations (Psychological Well-Being dimension) vs. Balanced positive relations was evaluated on Cardiac events in non-participants of secondary prevention (p=0.031). Among depressed acute coronary syndrome patients who did not participate in secondary prevention, impaired positive relations were associated with a significantly higher frequency of cardiac events (50% vs 13%).
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