Key result
Peak postoperative troponin T levels ≥0.30 ng/mL were associated with higher 30-day mortality compared to ≤0.01 ng/mL (16.9% vs 1.0%; aHR 10.48, 95% CI 6.25-16.62).
Why the study?
Does elevated postoperative troponin T predict 30-day mortality in adults undergoing noncardiac surgery?
Cohort (n=15,133)
Yes
Does elevated postoperative troponin T predict 30-day mortality in adults undergoing noncardiac surgery?
Hazard Ratio: 10.48 (95% CI 6.25–16.62)
Absolute Event Rate: 16.9% vs 1%
Routine measurement of troponin T in the first 3 days after noncardiac surgery provides significant incremental prognostic value for identifying patients at high risk of 30-day mortality.
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Peak postoperative troponin T identifies higher 30-day mortality risk after noncardiac surgery; leaves open whether troponin-guided interventions improve outcomes.
Devereaux et al. (2012) conducted a cohort in Noncardiac surgery (n=15,133). Peak postoperative troponin T (TnT) ≥ 0.30 ng/mL vs. Peak TnT ≤ 0.01 ng/mL was evaluated on 30-day mortality (aHR 10.48, 95% CI 6.25-16.62). Peak postoperative troponin T levels ≥0.30 ng/mL were associated with higher 30-day mortality compared to ≤0.01 ng/mL (16.9% vs 1.0%; aHR 10.48, 95% CI 6.25-16.62).
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