Key result
Atrioventricular simultaneous pacing shortened the effective refractory period of the concealed accessory pathway compared to ventricular pacing alone (from 341.7 to 312.5 msec with high right atrium pacing).
Why the study?
Does AV simultaneous pacing compared to ventricular pacing alone alter the effective refractory period of the concealed accessory pathway in patients with concealed WPW syndrome?
Does AV simultaneous pacing compared to ventricular pacing alone alter the effective refractory period of the concealed accessory pathway in patients with concealed WPW syndrome?
AV simultaneous pacing shortens the refractoriness of the concealed accessory AV pathway, providing electrophysiological evidence of anterograde concealed conduction.
Refines concealed WPW mechanisms; leaves open any impact on management or ablation pending validation.
Anterograde concealed conduction into the concealed accessory atrioventricular (AV) pathway has been postulated to be one of the factors preventing the reciprocating process via the accessory pathway in patients with the concealed Wolff-Parkinson-White(WPW) syndrome but its presence has not been documented. To demonstrate the occurrence of anterograde concealment, 12 patients with the concealed WPW syndrome were selected for study. A pacing protocol was designed in which the retrograde conduction of the ventricular extrastimulus over the accessory pathway was assessed during ventricular pacing alone (conventional method) and during the AV simultaneous pacing (simultaneous method); the results were then compared. When the high right atrium was simultaneously paced, the effective refractory period of the concealed accessory pathway shortened as compared with the conventional method in five of 12 patients (from 341.7 +/- 110.8 to 312.5 +/- 108.2 msec, n = 12), whereas, it decreased in all patients studied when the coronary sinus near the accessory pathway was simultaneously paced (from 375.7 +/- 135.0 to 287.1 +/- 116.1 msec, n = 7). These results demonstrate that the AV simultaneous pacing frequently shortens the refractoriness of the concealed accessory AV pathway and such facilitation seems to be well explained by the probable anterograde concealment in it and peeling back of the refractory barrier.
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Suzuki et al. (1989) studied Concealed Wolff-Parkinson-White (WPW) syndrome (n=12). Atrioventricular (AV) simultaneous pacing vs. Ventricular pacing alone (conventional method) was evaluated on Effective refractory period of the concealed accessory pathway. Atrioventricular simultaneous pacing shortened the effective refractory period of the concealed accessory pathway compared to ventricular pacing alone (from 341.7 to 312.5 msec with high right atrium pacing).
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