Key result
Premortem coronary arteriography accurately indicated atherosclerotic narrowing (7% discrepancy), but decreased segmental wall motion frequently (41%) did not indicate a structural myocardial lesion.
Why the study?
How accurately do clinical coronary arteriograms and left ventriculograms correlate with postmortem coronary anatomy and myocardial pathology?
Observational (n=28)
How accurately do clinical coronary arteriograms and left ventriculograms correlate with postmortem coronary anatomy and myocardial pathology?
Premortem coronary arteriography generally indicates atherosclerotic narrowing accurately, but decreased segmental wall motion frequently does not indicate a structural myocardial lesion, possibly reflecting ischemia or abnormal ventricular topography.
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Arteriography reliably detects coronary narrowing, but wall motion reduction often lacks structural correlate; challenges assumptions equating hypokinesis with fixed lesions.
Hutchins et al. (1977) conducted an observational in Ischemic and/or valvular heart disease (n=28). Premortem coronary arteriography and left ventriculography vs. Postmortem myocardial pathology was evaluated on Discrepancies in lumenal occlusion and wall motion compared to postmortem pathology. Premortem coronary arteriography accurately indicated atherosclerotic narrowing (7% discrepancy), but decreased segmental wall motion frequently (41%) did not indicate a structural myocardial lesion.