Key result
A genetic risk score comprising 12 single-nucleotide polymorphisms may identify individuals at increased risk for atrial fibrillation and help stratify ablation therapy or periinterventional management.
Population
Individuals with atrial fibrillation (including familial cases and lone atrial fibrillation)
Design
Review
Authors
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May support genetic AF risk stratification; leaves open prospective validation before clinical use.
Genetic variants, including a 12-SNP risk score, play a significant role in atrial fibrillation risk and may eventually guide therapeutic strategies like ablation.
Hayashi et al. (2016) conducted a review in Atrial fibrillation. Genetic variants was evaluated. A genetic risk score comprising 12 single-nucleotide polymorphisms may identify individuals at increased risk for atrial fibrillation and help stratify ablation therapy or periinterventional management.
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