Key result
Diabetes is linked to incident depressive symptoms, while CVD and multimorbidity track with persistent symptoms.
Why the study?
The study aimed to assess associations between chronic diseases and incident and persistent depressive symptoms in ageing adults in South Africa.
Do chronic conditions increase the risk of incident and persistent depressive symptoms in aging adults in rural South Africa?
Cohort (n=5,059)
Do chronic conditions increase the risk of incident and persistent depressive symptoms in aging adults in rural South Africa?
Chronic conditions, particularly diabetes and cardiovascular diseases, are significantly associated with the onset and persistence of depressive symptoms in aging African populations.
Answers are grounded in this paper and cite their sources.
Diabetes and multimorbidity may warrant depressive symptom monitoring in rural South African elders; extends prior associations but remains hypothesis-generating.
The study aimed to assess associations between chronic diseases and incident and persistent depressive symptoms (DSs) in a cohort study of ageing adults in South Africa. Participants in the baseline survey (in 2014/2015) were 5,059 persons (≥40 years) and at follow-up 4,176 (in 2018/2019). DSs were measured with the Center for Epidemiological Studies Depression scale. Logistic regression was used to estimate the associations between chronic conditions and incident and persistent DS. The prevalence of DS at baseline was 15.5%, incident DS (without DS and/or PTSD at baseline) was 25.1% and persistent DS (DS at both baseline and follow-up) was 4.8%. In unadjusted logistic regression analysis, diabetes had higher odds of incident DS. Participants with baseline heart attack/stroke/angina, dyslipidemia, tuberculosis, chronic bronchitis, kidney disease and three or more chronic conditions had a higher probability of persistent DS. In conclusion, of the eight chronic conditions evaluated, only diabetes (in unadjusted analysis) was associated with incident DS, and five chronic conditions (heart attack/stroke/angina, dyslipidaemia, tuberculosis, chronic bronchitis and kidney disease) and three or more chronic conditions were associated with persistent DS.
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Pengpid et al. (2023) conducted a cohort in Depressive symptoms (DS) (n=5,059). Chronic conditions (diabetes, heart attack/stroke/angina, dyslipidemia, tuberculosis, chronic bronchitis, kidney disease) vs. Absence of specific chronic conditions was evaluated on Incident and persistent depressive symptoms measured by the Center for Epidemiological Studies-Depression (CES-D) scale. Diabetes was positively associated with incident depressive symptoms, while cardiovascular diseases, dyslipidemia, tuberculosis, chronic bronchitis, kidney disease, and multimorbidity were associated with persistent depressive symptoms.
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