Depressive symptoms predict incident chronic disease burden 10 years later: Findings from the English Longitudinal Study of Ageing (ELSA)
Key result
Baseline depressive symptoms were associated with a greater incident chronic illness burden 10 years later (IRR 1.05; 95% CI 0.05-0.21; p=0.003).
Why the study?
Do baseline depressive symptoms predict incident chronic illness burden over 10 years in older adults without prevalent chronic disease?
Population
2472 participants from the English Longitudinal Study of Ageing, mean age 62.88, 50.8% female, without…
Design
Cohort
Follow-up
10 years
Authors
Discussion
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Member takes
Implication
May warrant monitoring depressive symptoms in healthy older adults; leaves open whether treatment reduces future chronic illness burden.
Study Design
Type
Cohort (n=2,472)
Structured PICO
Do baseline depressive symptoms predict incident chronic illness burden over 10 years in older adults without prevalent chronic disease?
P
Population
2,472 older adults (mean age 62.9 years, 50.8% female) free of prevalent chronic illness at baseline, followed for 10 years.
E
Exposure
Depressive symptoms measured using the Centre for Epidemiological Studies Depression (CES-D) scale at baseline
O
Outcome
Incident chronic illness burden (the sum of illnesses reported) over 10 years follow-upcomposite
Main Result
Relative Risk: 1.05 (95% CI 0.05–0.21)
p-value: p=0.003
Baseline depressive symptoms in physically healthy older adults independently predict a greater burden of incident chronic illnesses over the subsequent 10 years.
Cite This Study
Poole et al. (2018) conducted a cohort in Depressive symptoms (n=2,472). Depressive symptoms (CES-D score) was evaluated on Incident chronic illness burden (sum of illnesses reported) (IRR 1.05, 95% CI 0.05-0.21, p=0.003). Baseline depressive symptoms were associated with a greater incident chronic illness burden 10 years later (IRR 1.05; 95% CI 0.05-0.21; p=0.003).