Key result
Guidance of percutaneous pulmonary valve implantation using MRI-derived 3D roadmaps resulted in significantly lower weight-adjusted radiation exposure compared to CT-derived roadmaps (57.6 vs 162.3 cGy·cm2/kg, p=0.014).
Why the study?
Does direct 2D-3D image fusion using MRI or CT datasets improve procedural metrics in patients undergoing percutaneous pulmonary valve implantation?
Observational (n=24)
Yes
Does direct 2D-3D image fusion using MRI or CT datasets improve procedural metrics in patients undergoing percutaneous pulmonary valve implantation?
Direct 2D-3D image fusion using MRI or CT datasets is feasible and facilitates percutaneous pulmonary valve implantation, with MRI offering lower radiation exposure and CT potentially reducing contrast use and procedural time.
Answers are grounded in this paper and cite their sources.
Direct 2D-3D fusion appears feasible for PPVI guidance; leaves open whether outcomes improve versus standard 2D angiography.
INTRODUCTION: Until recently, two-dimensional (2D) angiography was the mainstay of guidance for percutaneous pulmonary valve implantation (PPVI). Recent advances in fusion software have enabled direct fusion of pre-intervention imaging, magnetic resonance imaging (MRI) or computed tomography (CT) scans, to create a reliable three-dimensional (3D) roadmap for procedural guidance. AIM: To report initial two-center experience with direct 2D-3D image fusion for live guidance of PPVI with MRI- and CT-derived 3D roadmaps. MATERIAL AND METHODS: We performed a prospective study on PPVIs guided with the new fusion imaging platform introduced in the last quarter of 2015. Successful 2D-3D registration was performed in all but 1 patient. Six (27%) patients required intra-procedural readjustment of the 3D roadmap due to distortion of the anatomy after introduction of a stiff wire. Twenty-one (95%) interventions were successful in the application of 3D imaging. Patients in the CT group received less contrast volume and had a shorter procedural time, though the differences were not statistically significant. Those in the MRI group had significantly lower weight adjusted radiation exposure. CONCLUSIONS: With intuitive segmentation and direct 2D-3D fusion of MRI or CT datasets, VesselNavigator facilitates PPVI. Our initial data show that utilization of CT-derived roadmaps may lead to less contrast exposure and shorter procedural time, whereas application of MRI datasets may lead to lower radiation exposure.
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Góreczny et al. (2018) conducted an observational in Right ventricular outflow tract dysfunction (n=24). MRI-derived 3D roadmap guidance vs. CT-derived 3D roadmap guidance was evaluated on Weight-adjusted dose area product (cGy·cm2/kg) (p=0.014). Guidance of percutaneous pulmonary valve implantation using MRI-derived 3D roadmaps resulted in significantly lower weight-adjusted radiation exposure compared to CT-derived roadmaps (57.6 vs 162.3 cGy·cm2/kg, p=0.014).
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