Key result
Quality of life scales demonstrate internal validity, reliability, and external validity, with their most appropriate applicability in long-term trials with antidepressants for major depression.
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Quality of life scales are valid and reliable tools, particularly suited for long-term trials evaluating antidepressants in major depression.
In randomized clinical trials in patients with major depression quality of life is considered as an important dimension of treatment outcome in relation to clinical efficacy and safety. The internal validity, reliability, as well as external validity of quality of life scales have been analysed. It is concluded that such scales have their most appropriate applicability in medicine and long-term trials with antidepressants.
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Per Bech (1996) conducted a review in Major depression. Quality of life scales was evaluated. Quality of life scales demonstrate internal validity, reliability, and external validity, with their most appropriate applicability in long-term trials with antidepressants for major depression.
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