Key result
High-intensity interval training significantly improved peak V̇O2 compared with usual care (MD 2.11 ml/kg/min; 95% CI 0.75-3.47; p=0.002), with comparable effects to MICT.
Why the study?
The study was conducted to compare the effects of high-intensity interval training versus moderate-intensity continuous training and usual care on cardiorespiratory fitness and CPET indices in cancer patients and survivors.
Does high-intensity interval training improve cardiorespiratory fitness compared to moderate-intensity continuous training or usual care in cancer patients and survivors?
Comparison
HIIT vs MICT and usual care
Design
Systematic review and meta-analysis of controlled trials
Authors
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Supports HIIT in cancer exercise programs; confirms benefits over usual care with effects comparable to MICT.
Meta-Analysis (n=516)
Does high-intensity interval training improve cardiorespiratory fitness compared to moderate-intensity continuous training or usual care in cancer patients and survivors?
Mean Difference: 2.11 (95% CI 0.75–3.47)
p-value: p=.002
High-intensity interval training is safe, well-tolerated, and significantly improves cardiorespiratory fitness compared to usual care in cancer patients and survivors, with effects comparable to moderate-intensity continuous training.
Wallen et al. (2020) conducted a meta-analysis in cancer patients and survivors (n=516). High-intensity interval training (HIIT) vs. Moderate-intensity continuous training (MICT) and usual care (UC) was evaluated on cardiorespiratory fitness (peak V̇O2) (MD 2.11 ml kg−1 min−1, 95% CI 0.75-3.47, p=.002). High-intensity interval training significantly improved peak V̇O2 compared with usual care (MD 2.11 ml/kg/min; 95% CI 0.75-3.47; p=0.002), with comparable effects to MICT.
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