Answers are grounded in this paper and cite their sources.
Set it and forget it: The combination of feedback control and continuous-flow operations in microreactors (see picture) enables online and fully automated reaction optimization. A Heck reaction demonstrates the potential for rapid multivariable reaction optimization while requiring a minimal amount of material. Optimal conditions are quickly scaled-up by a factor of 50.
No takes yet. Share an insight, caveat, or question.
McMullen et al. (2010) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: