Key result
Pulmonary artery catheter-guided rapid ventricular pacing successfully provided controlled hypotension with a mean arterial pressure of 47 mmHg without technical complications during thoracic endograft deployment.
Why the study?
Does PAC guided transvenous rapid ventricular pacing safely provide deliberate hypotension in patients undergoing thoracic endograft deployment?
Observational (n=39)
No
Does PAC guided transvenous rapid ventricular pacing safely provide deliberate hypotension in patients undergoing thoracic endograft deployment?
PAC-guided transvenous rapid ventricular pacing is a feasible and effective technique for inducing deliberate hypotension during thoracic endograft deployment.
PAC-guided rapid ventricular pacing appears feasible for controlled hypotension in TEVAR; leaves open comparative safety and efficacy versus alternatives.
Deliberate hypotension facilitates precise deployment of endovascular stent grafting in the thoracic aorta. We describe a practical technique using pulmonary artery catheter (PAC) guided transvenous rapid ventricular pacing via transjugular approach and delineate pertinent anesthetic considerations. Anesthesiologists performed PAC guided rapid ventricular pacing in thirty-nine (39) patients (27 men and 12 women, mean age 74 11 years) undergoing thoracic endograft deployment for aneurysm repair. Patient characteristics, hemodynamic parameters, pacing rate, and number of pacing events were recorded. Post-operative complications were evaluated. PAC guided rapid ventricular pacing successfully provided controlled hypotension without technical complications. Mean pacing rate was 177 17 beats/min with an average of 2.6 2 pacing events/surgical procedure. Average pacing duration was 34 29 seconds (MAP of 47 5 mmHg). One intraoperative death occurred in a patient with severe valvular heart disease. In all other cases, recovery time to baseline hemodynamics was short. Postoperative complications included atrial fibrillation in five patients (12%), elevated troponin levels in eight (21%), and stroke in three (8%). No patients had PAC related complications.
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Wittwer et al. (2014) conducted an observational in Thoracic aortic aneurysm (n=39). Pulmonary artery catheter guided rapid ventricular pacing was evaluated on Mean arterial pressure during pacing. Pulmonary artery catheter-guided rapid ventricular pacing successfully provided controlled hypotension with a mean arterial pressure of 47 mmHg without technical complications during thoracic endograft deployment.
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