Key result
Pre-hospital diagnosis of STEMI with direct referral to PCI was associated with a >45 minute reduction in treatment delay (P=0.001) and reduced mortality in the cardiogenic shock subgroup.
Why the study?
Does pre-hospital diagnosis with direct referral to PCI reduce treatment delay and improve survival in STEMI patients?
Population
658 STEMI patients referred for primary PCI, including a subgroup with cardiogenic shock (n=80)
Comparison
Pre-hospital diagnosis of STEMI with direct… vs Diagnosis at the interventional hospital…
Design
Cohort
Follow-up
in-hospital
Authors
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May support expedited pre-hospital STEMI pathways in shock; leaves open need for randomized confirmation of mortality benefit.
Cohort (n=658)
No
Does pre-hospital diagnosis with direct referral to PCI reduce treatment delay and improve survival in STEMI patients?
Effect estimate: >45 min reduction
p-value: p=0.001
Pre-hospital diagnosis of STEMI with direct referral to PCI significantly reduces treatment delays and may offer substantial survival benefits for high-risk patients presenting with cardiogenic shock.
Ortolani et al. (2006) conducted a cohort in ST-elevation myocardial infarction (STEMI) (n=658). Pre-hospital diagnosis and direct transportation vs. Diagnosis at interventional hospital emergency department or local hospitals was evaluated on Treatment delay (>45 min reduction, p=0.001). Pre-hospital diagnosis of STEMI with direct referral to PCI was associated with a >45 minute reduction in treatment delay (P=0.001) and reduced mortality in the cardiogenic shock subgroup.
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