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Patients with Alzheimer's disease exhibit a reduction in optic nerve fibers and have a threefold greater odds of a larger optic cup-to-disc ratio compared to healthy controls. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

November 28, 2006Open Access

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Reduction of optic nerve fibers in patients with Alzheimer disease identified by laser imaging

HDHelen V. Danesh‐MeyerUniversity of Auckland HBH. BirchUniversity of Auckland JKJudy Y.F. KuUniversity of Auckland

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Resumen

In this case-control study, we compared the optic nerves (ONs) by clinical examination and scanning laser ophthalmoscopy (SLO) of 40 patients with Alzheimer disease (AD) and 50 controls. There was a reduction in the number of ON fibers in patients with AD, with a threefold greater odds ratio for a larger optic cup-to-disc ratio in patients with AD.

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Cite This Study

Danesh‐Meyer et al. (Tue,) studied this question.

synapsesocial.com/papers/6a638fb19a2e487662c20972 https://doi.org/https://doi.org/10.1212/01.wnl.0000244490.07925.8b

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