Key result
In patients with cryptogenic stroke, being in the upper quartile of supraventricular premature beats (>14.1/h) predicted future atrial fibrillation (RR 4.0; 95% CI 1.1-14.6; P=0.04).
Why the study?
Do frequent supraventricular premature beats and short atrial runs predict future atrial fibrillation in patients with cryptogenic stroke?
Population
70 consecutive patients with acute cryptogenic stroke, mean age 59±13 years
Comparison
Upper quartile of supraventricular premature… vs Lower quartiles of supraventricular premature…
Design
Cohort
Follow-up
mean 536±212 days
Authors
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May identify cryptogenic stroke patients for intensified AF monitoring; hypothesis-generating, requiring prospective validation before practice change.
Cohort (n=70)
Do frequent supraventricular premature beats and short atrial runs predict future atrial fibrillation in patients with cryptogenic stroke?
Relative Risk: 4 (95% CI 1.1–14.6)
p-value: p=0.04
A high burden of supraventricular premature beats and short atrial runs on 24-hour ECG strongly predicts the future occurrence of atrial fibrillation in patients with cryptogenic stroke.
Kochhäuser et al. (2014) conducted a cohort in cryptogenic stroke (n=70). High frequency of supraventricular premature beats (SPBs >14.1/h) vs. Lower frequency of SPBs was evaluated on future atrial fibrillation (RR 4.0, 95% CI 1.1-14.6, p=0.04). In patients with cryptogenic stroke, being in the upper quartile of supraventricular premature beats (>14.1/h) predicted future atrial fibrillation (RR 4.0; 95% CI 1.1-14.6; P=0.04).
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