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Rotavirus A (RVA; family Sedoreoviridae , taxon species Rotavirus alphagastroenteritidis ) is a non-enveloped double-stranded RNA virus that has been reported from both diarrheic and non-diarrheic pigs worldwide. With significant morbidity and mortality rates in neonatal piglets, rotavirus-associated illness adds enormous economic losses to the pig industry. Furthermore, the proximity of humans and pigs facilitates cross-species infection, which results in the formation of novel strains through genetic recombination. We aimed to detect and characterize porcine RVA (PRVA) in Haryana, India, using reverse-transcription PCR targeting the VP6 , VP4 , and VP7 genes. We detected 46 of 137 (34%) rectal swab samples as positive for PRVA, including 27 of 63 (43%) from diarrheic pigs and 19 of 74 (26%) from non-diarrheic pigs. In addition, phylogenetic analysis revealed the presence of genotypes I1, I5, P13, P6, G11, G4, and combinations of G4P6, G4P13, and G11P13 in the pig population of Haryana. G4P6 was the most common combination found, followed by G11P13 and G4P13. Genotype G11 and the combinations G4P13 and G11P13 have not been reported previously in pigs, in India, to our knowledge. Our finding of various genotypes, and their genetic proximity to human RVA, indicates their potential zoonotic importance.
Sheoran et al. (Mon,) studied this question.