Key result
Rotavirus was detected in 36.7% of hospitalized children with severe diarrhoea, 22.0% of outpatients, and 1.7% of controls, with no association between disease severity and specific genotypes.
Population
234 children with or without acute diarrhoea
Design
Cross-sectional
Authors
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High rotavirus detection in severe pediatric diarrhea supports vaccination; leaves open genotype-severity links for prospective study.
Case-Control (n=234)
Absolute Event Rate: 36.7% vs 1.7%
Rotavirus is a significant cause of acute diarrhoea in children in São Paulo, with G1 and G5 being the predominant VP7 genotypes, though strain type does not correlate with disease severity.
Carmona et al. (2004) conducted a case-control in Acute diarrhoea (n=234). Severe acute diarrhoea vs. Children without acute diarrhoea (controls) was evaluated on Rotavirus detection. Rotavirus was detected in 36.7% of hospitalized children with severe diarrhoea, 22.0% of outpatients, and 1.7% of controls, with no association between disease severity and specific genotypes.
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