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Abstract Aziridine is the smallest nitrogen‐containing heterocycle. It is not only an important synthetic target but also a useful building block for constructing nitrogen‐containing biologically active molecules. Due to the unique properties and reactivity of aziridine, interest in its applications in synthetic organic chemistry and pharmaceutical industry has grown rapidly in recent years. This review highlights the significance of aziridines as end products and/or precursors of medicinally relevant molecules, scope and synthetic applications of aziridines in pharmaceutical industry in recent decades.
Ju et al. (Tue,) studied this question.