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Diagnosis and therapy in one: Many prevalent diseases, such as atherosclerosis, could be efficiently treated by localized, macrophage-targeted therapies. A biocompatible nanoparticle with high macrophage avidity is presented; the nanoparticle has magnetic and fluorescence, as well as therapeutic, imaging functionalities. Multimodal detection and exquisite phototoxicity to macrophages under appropriate illumination is shown (see image).
McCarthy et al. (Tue,) studied this question.