Key result
Antibiotic therapy with penicillin and gentamycin successfully treated infective endocarditis following transcatheter pulmonary valve implantation, with complete vegetation resolution at 12 months.
Why the study?
Infective endocarditis is a lethal complication in patients with congenital heart disease.
Case Report (n=1)
No
Transcatheter pulmonary valve-related infective endocarditis can be successfully managed with targeted antibiotic therapy alone without requiring surgical intervention.
IE after percutaneous pulmonary valve implantation warrants clinical vigilance in congenital heart disease; leaves open incidence and prevention questions for larger cohorts.
Infective endocarditis (IE) is a lethal complication inpatients with congenital heart disease. We report a case of percutaneous implanted pulmonary valve IE in a 49-year-old female. She underwent a previous surgery for tetralogy of Fallot with transannular patching of the right ventricular outflow tractat the age of 18 years. Echocardiography showed chronic moderate to severe pulmonary regurgitation with right heart enlargement. She underwent transcatheter pulmonary valve implantation with a 26 mm Venus-P valve (Venus Medtech, Shanghai, China) in order to release pulmonary insufficiency. Two months after implantation, she presented with recurrent chills and febrile for one week, and percutaneous implanted pulmonary valve IE was diagnosed. According to the antibiotic susceptibility test, she was given penicillin and gentamycin. At 12 months follow-up, TTE showed vegetation completely disappeared and the valve functioned normally. The patient recovered uneventfully without any complications like recurrent IE.
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Wang et al. (2019) conducted a case report in Infective endocarditis after transcatheter pulmonary valve implantation (n=1). Antibiotic therapy (penicillin and gentamycin) was evaluated on Resolution of infective endocarditis and valve function. Antibiotic therapy with penicillin and gentamycin successfully treated infective endocarditis following transcatheter pulmonary valve implantation, with complete vegetation resolution at 12 months.
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