What is the clinical evidence from this study?

Study design: Observational. Population: Infective endocarditis (n=155). Intervention: Intravascular catheters and implanted cardiac devices. Primary outcome: Source of infection and 90-day mortality.

What question did this study set out to answer?

This research aims to explore the impact of intravascular and cardiac devices on infective endocarditis incidence and outcomes.

June 10, 2012Scandinavian Journal of Infectious Diseases

Device-related infective endocarditis, with special consideration of implanted intravascular and cardiac devices in a predominantly male population

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Key result

Intravascular catheters (17.4%) and implanted cardiac devices (10.3%) were common sources of infection in 155 patients with infective endocarditis, which had a 90-day mortality of 22.5%.

Population

155 patients with 'definite' or 'possible' infective endocarditis as per the modified Duke criteria…

Design

Cohort

Follow-up

90 days

Authors

IRIngrid RoigInfectious Disease Consultants RDRabih O. DarouicheUniversity of Michigan DMDaniel M. MusherMichael E. DeBakey VA Medical Center

Discussion

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Implication

Device sources merit clinical vigilance in IE evaluation; extends observational data but leaves causal links and prevention open.

Key Points

This research aims to explore the impact of intravascular and cardiac devices on infective endocarditis incidence and outcomes.
Conducted a retrospective review of hospital records from 1997 to 2007.
Included patients diagnosed with 'definite' or 'possible' infective endocarditis based on modified Duke criteria.
Assessed the presence of intravascular and implanted devices prior to infective endocarditis diagnosis.
Out of 155 identified cases of infective endocarditis, 10.3% were linked to implanted cardiac devices.
Central venous catheters were identified as the source of infection in 17.4% of cases.
Mortality was 31.9% among patients with infective endocarditis caused by MRSA.

Study Design

Type

Observational (n=155)

Structured PICO

Population

155 patients with definite or possible infective endocarditis evaluated retrospectively over a 10-year period to assess device-related infections.

Outcome

Source of infection, involved structures, causative organisms, and 90-day mortalityhard clinical

Intravascular catheters and cardiac implantable devices are significant sources of infective endocarditis, frequently involving S. aureus and carrying high mortality.

Cite This Study

Roig et al. (2012) conducted an observational in Infective endocarditis (n=155). Intravascular catheters and implanted cardiac devices was evaluated on Source of infection and 90-day mortality. Intravascular catheters (17.4%) and implanted cardiac devices (10.3%) were common sources of infection in 155 patients with infective endocarditis, which had a 90-day mortality of 22.5%.

synapsesocial.com/papers/6a63d688f3f956990ff2dea1 https://doi.org/10.3109/00365548.2012.678882

Topics

Infective endocarditis

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Device-related infective endocarditis, with special consideration of implanted intravascular and cardiac devices in a predominantly male population

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Topics

Device-related infective endocarditis, with special consideration of implanted intravascular and cardiac devices in a predominantly male population

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

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