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November 1, 2005Clinical Cancer Research

Allogeneic Transplant with Reduced Intensity Conditioning Regimens may Overcome the Poor Prognosis of B-Cell Chronic Lymphocytic Leukemia with Unmutated Immunoglobulin Variable Heavy-Chain Gene and Chromosomal Abnormalities (11q− and 17p−)

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Authors

DCDolores CaballeroAbbVie (United States)JGJosé A. García‐MarcoHospital Universitario Puerta de Hierro MajadahondaRMRodrigo MartinoUniversitat Autònoma de Barcelona

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Caballero et al. (2005) studied this question.

synapsesocial.com/papers/6a63d86bb28cf853587a74eahttps://doi.org/10.1158/1078-0432.ccr-05-0941
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Graft-versus-leukemia activity may overcome therapeutic resistance of chronic lymphocytic leukemia with unmutated immunoglobulin variable heavy-chain gene status: implications of minimal residual disease measurement with quantitative PCR2004 · 170 citations
  2. 2HLA-Identical Sibling Bone Marrow Transplantation in Younger Patients with Chronic Lymphocytic Leukemia1996 · 248 citations
  3. 3Engraftment of Allogeneic Hematopoietic Progenitor Cells With Purine Analog-Containing Chemotherapy: Harnessing Graft-Versus-Leukemia Without Myeloablative Therapy1997 · 1,152 citations
  4. 4Autologous and allogeneic bone marrow transplantation for poor prognosis patients with B-cell chronic lymphocytic leukemia1993 · 163 citations
  5. 5Evidence of a Graft-Versus-Leukemia Effect in Chronic Lymphocytic Leukemia After Reduced-Intensity Conditioning and Allogeneic Stem-Cell Transplantation: The Cooperative German Transplant Study Group2003 · 251 citations