Key result
Transcatheter tricuspid valve intervention using coaptation devices demonstrates procedural feasibility, early safety, and satisfactory mid-term outcomes for the treatment of severe tricuspid regurgitation.
Why the study?
Transcatheter tricuspid valve intervention has emerged as an alternative for severe tricuspid regurgitation, prompting a review of clinical evidence, device designs, procedural steps, and outcomes for coaptation devices.
Transcatheter coaptation devices offer a feasible and minimally invasive alternative for reducing severe tricuspid regurgitation and improving symptoms in high-risk patients.
TTVI may support severe TR treatment; leaves open need for RCTs to confirm safety and durability.
Transcatheter tricuspid valve intervention (TTVI) has recently emerged as an alternative for the treatment of severe tricuspid regurgitation (TR). Multiple percutaneous devices have been developed in the last decade with promising early results. Among them, the coaptation devices are designed to reduce TR severity by valve leaflet plication or occupying the regurgitant orifice with a spacer. To date, the MitraClip/TriClip devices (Abbott, Santa Clara, CA, USA), the PASCAL system (Edwards Lifesciencies, Irvine, CA, USA), and the FORMA device (Edwards Lifesciencies, Irvine, CA, USA) have been used as coaptation devices for treating severe TR. The present document aimed to review the clinical evidence on coaptation devices in the field of TTVI, describing its design characteristics, main procedural steps, and early and mid-term outcomes.
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Muntané‐Carol et al. (2020) conducted a review in Severe tricuspid regurgitation. Coaptation devices (MitraClip/TriClip, PASCAL, FORMA) was evaluated. Transcatheter tricuspid valve intervention using coaptation devices demonstrates procedural feasibility, early safety, and satisfactory mid-term outcomes for the treatment of severe tricuspid regurgitation.
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