Key result
Boxer dogs with ARVC exhibited significantly greater right ventricular wall fatty replacement than controls (40.4% vs 13.8%, P<0.001), serving as a spontaneous animal model for the human disease.
Case-Control (n=23)
Absolute Event Rate: 40.4% vs 13.8%
p-value: p=<0.001
No takes yet. Share an insight, caveat, or question.
May model human ARVC in boxer dogs; leaves open validation for mechanistic or therapeutic studies.
Basso et al. (2004) conducted a case-control in Arrhythmogenic right ventricular cardiomyopathy (ARVC) (n=23). Arrhythmogenic right ventricular cardiomyopathy (ARVC) vs. Controls was evaluated on Right ventricular wall area occupied by fatty replacement (p=<0.001). Boxer dogs with ARVC exhibited significantly greater right ventricular wall fatty replacement than controls (40.4% vs 13.8%, P<0.001), serving as a spontaneous animal model for the human disease.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: