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Trimercaptotriazine-modified gold nanoparticles exhibit strong SERS effects, yielding vibrational profiles very sensitive to the presence of heavy metal ions. Because of the contrasting response observed for selected vibrational bands in the SERS profiles, they provide useful nanoprobes for Hg2+ and Cd2+ ions, allowing direct quantitative assays by employing relative peak intensity ratios instead of using internal standards.
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Zamarion et al. (2008) studied this question.
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