Key points are not available for this paper at this time.
An enantioselective approach to bicyclo2.2.2octenone structures utilizing a copper-mediated asymmetric oxidative dearomatization/4 + 2 dimerization cascade is described. The total synthesis and absolute stereochemistry reassignment of (+)-aquaticol has been achieved using the methodology.
Dong et al. (Tue,) studied this question.