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February 1, 2015Journal of Clinical Neurophysiology

Cardiac and Autonomic Mechanisms Contributing to SUDEP

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Key result

Cardiac and autonomic alterations, particularly in longstanding and refractory epilepsy, may compromise cardiorespiratory function and predispose patients to sudden unexpected death in epilepsy.

Population

Patients with epilepsy, particularly those with longstanding and medication-refractory epilepsy

Design

Review

Authors

ABAdriana Bermeo‐OvalleRush University Medical CenterJKJeffrey D. KennedyUniversity of California, DavisSSStephan SchueleNorthwestern University

Discussion

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Implication

May warrant autonomic monitoring in longstanding epilepsy; leaves open causal role in SUDEP and targeted interventions.

Structured PICO

P
Population
Patients with epilepsy, particularly those with longstanding and medication-refractory epilepsy

Cardiac and autonomic alterations in epilepsy, particularly in longstanding and refractory cases, may predispose patients to sudden unexpected death in epilepsy (SUDEP).

Cite This Study

Bermeo‐Ovalle et al. (2015) conducted a review in Sudden unexpected death in epilepsy (SUDEP). Cardiac and autonomic alterations was evaluated. Cardiac and autonomic alterations, particularly in longstanding and refractory epilepsy, may compromise cardiorespiratory function and predispose patients to sudden unexpected death in epilepsy.

synapsesocial.com/papers/6a63f6c394d8bae735b37d55https://doi.org/10.1097/wnp.0000000000000155
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