This research shows a novel reaction converting triazoles into pyrroles using a Rh-based catalyst, indicating valuable synthetic utility.
The first transannulation of 1,2,3-triazoles with terminal alkynes into pyrroles is reported. The reaction proceeds in the presence of a Rh(2)(oct)(4)/AgOCOCF(3) binary catalyst system providing a straightforward approach to 1,2,4-trisubstituted pyrroles in good to excellent yields.
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Chattopadhyay et al. (2011) studied this question.
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