Key result
Type-D personality was an independent prognostic factor for the development of cancer in men with established coronary heart disease (13% vs 2%; OR 7.2, 95% CI 2.9-18.1).
Why the study?
Does type-D personality increase the risk of cancer in men with coronary heart disease?
Cohort (n=246)
Does type-D personality increase the risk of cancer in men with coronary heart disease?
Odds Ratio: 7.2 (95% CI 2.9–18.1)
Absolute Event Rate: 13% vs 2%
p-value: p=0.002
Type-D personality is a strong independent prognostic factor for the development of cancer in men with established coronary heart disease.
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Type-D personality may flag higher cancer incidence in CHD; leaves open causal links and screening utility pending larger trials.
Johan Denollet (1998) conducted a cohort in Coronary heart disease (n=246). Type-D personality (distressed personality) vs. Non-type-D personality was evaluated on Incidence of cancer (OR 7.2, 95% CI 2.9-18.1, p=0.002). Type-D personality was an independent prognostic factor for the development of cancer in men with established coronary heart disease (13% vs 2%; OR 7.2, 95% CI 2.9-18.1).
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