Key result
Takotsubo cardiomyopathy is a reversible left ventricular dysfunction typically triggered by stress, presenting similarly to acute coronary syndrome but with a generally favorable prognosis.
Takotsubo cardiomyopathy is a reversible stress-induced cardiomyopathy that mimics acute coronary syndrome but generally has a favorable prognosis.
Stress cardiomyopathy mimics ACS with reversible LV dysfunction; review leaves open true prevalence and management.
Stress cardiomyopathy is characterised by reversible left ventricular dysfunction. It simulates an acute coronary syndrome (ACS), presenting with precordial pain or dyspnoea, changes of the ST segment, T wave, or QTc interval on electrocardiogram, and raised cardiac enzymes. Typical findings are disturbances of segmental contractility (apical hypokinesia or akinesia), with normal epicardial coronary arteries. The true prevalence is unknown, as the syndrome may be under-diagnosed; it is more common in postmenopausal women. There is usually a trigger in the form of physical or psychological stress. The electrocardiographic, echocardiographic, and ventriculographic changes resolve spontaneously over a variable period of time (from days to months). There are a number of pathophysiological theories, none of which has been shown to be definitive, suggesting that all of them may be involved to some extent. The prognosis is generally favourable, and recurrence is very rare.
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Rivera et al. (2011) conducted a review in Takotsubo cardiomyopathy. Takotsubo cardiomyopathy is a reversible left ventricular dysfunction typically triggered by stress, presenting similarly to acute coronary syndrome but with a generally favorable prognosis.
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