Why the study?
A consensus definition was needed to facilitate the study of the pathophysiology, clinical impact, potential treatment, and cardiovascular risk associated with orthostatic hypertension.
Provides a standardized consensus definition for orthostatic hypertension to facilitate future research and clinical identification of at-risk patients.
Standardizes orthostatic hypertension identification in practice; enables consistent future research on risks and management.
We propose a consensus definition of "an exaggerated orthostatic pressor response" in subjects in whom systolic blood pressure increases ≥20 mmHg when going from the supine to standing posture. This definition can be extended for seated to standing measurements. We reserve the term "orthostatic hypertension" if this pressor response leads to an upright systolic blood pressure ≥140 mmHg. We believe this consensus definition will help in the study of the pathophysiology, clinical impact, and potential treatment of these entities, and the identification of patients that are at greater cardiovascular risk.
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Jordan et al. (2022) conducted an editorial in Orthostatic hypertension. Consensus definition of orthostatic hypertension was evaluated. The consensus statement defines an exaggerated orthostatic pressor response as a systolic blood pressure increase of ≥20 mmHg upon standing, and orthostatic hypertension if upright SBP is ≥140 mmHg.